Notochordal-Cell-Derived Exosomes Induced by Compressive Load Inhibit Angiogenesis via the miR-140-5p/Wnt/β-Catenin Axis

Angiogenesis is a pathological signature of intervertebral disc degeneration (IDD). Accumulating evidence has shown that notochordal cells (NCs) play an essential role in maintaining intervertebral disc development and homeostasis with inhibitive effect on blood vessel in-growth. However, the anti-a...

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Detalhes bibliográficos

Principais autores:	Zhen Sun, Bing Liu, Zhi-Heng Liu, Wen Song, Dong Wang, Bei-Yu Chen, Jing Fan, Zhe Xu, Dan Geng, Zhuo-Jing Luo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-12-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	intervertebral disc notochordal cell exosome angiogenesis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253120303334
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