Reducing Glucokinase Activity to Enhance Insulin Secretion: A Counterintuitive Theory to Preserve Cellular Function and Glucose Homeostasis

Pancreatic beta-cells are the only cells in the body that can synthesize and secrete insulin. Through the process of glucose-stimulated insulin secretion, beta-cells release insulin into circulation, stimulating GLUT4-dependent glucose uptake into peripheral tissue. Insulin is normally secreted in p...

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Principais autores:	Nicholas B. Whitticar, Craig S. Nunemaker
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2020-06-01
סדרה:	Frontiers in Endocrinology
נושאים:	type 2 diabetes metabolic syndrome hyperinsulinemia beta cell pancreatic islet insulin
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fendo.2020.00378/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!