aFGF rescues high glucose-induced senescent fibroblasts and improves diabetic wound healing by regulating SIRT1/STAT3 pathway

Abstract In the wound of diabetic patients, Fibroblasts are extensively senescent and dysfunctional, resulting in prolonged skin wound healing time. The aim of this study was to investigate the impact of aFGF on diabetic wound healing and the senescence of fibroblasts induced by high glucose, and to...

Повний опис

Бібліографічні деталі

Автори:	Xiaoyang Wang, Meiqi Lu, Shanshan Jia, Jingjuan Zhang, Xiao Wang, Yongjun Qi, Nian Shi, Ya Jiao, Jie Zhao, Xiaochuan Wang, Jixun Zhang, Duyin Jiang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Nature Portfolio 2026-02-01
Серія:	Scientific Reports
Предмети:	Acidic fibroblast growth factor Diabetic wounds Fibroblast Senescence SASP
Онлайн доступ:	https://doi.org/10.1038/s41598-026-38480-0
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!