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Systematic association mapping identifies NELL1 as a novel IBD disease gene.

Crohn disease (CD), a sub-entity of inflammatory bowel disease (IBD), is a complex polygenic disorder. Although recent studies have successfully identified CD-associated genetic variants, these susceptibility loci explain only a fraction of the heritability of the disease. Here, we report on a multi...

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Uloženo v:
Hlavní autoři: Andre Franke, Jochen Hampe, Philip Rosenstiel, Christian Becker, Florian Wagner, Robert Häsler, Randall D Little, Klaus Huse, Andreas Ruether, Tobias Balschun, Michael Wittig, Abdou Elsharawy, Gabriele Mayr, Mario Albrecht, Natalie J Prescott, Clive M Onnie, Hélène Fournier, Tim Keith, Uwe Radelof, Matthias Platzer, Christopher G Mathew, Monika Stoll, Michael Krawczak, Peter Nürnberg, Stefan Schreiber
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2007-08-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000691&type=printable
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