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Topical use of tranexamic acid for antifibrinolysis in cardiac surgery with cardiopulmonary bypass: a randomized clinical study

Abstract Objective To assess the non-inferiority of topical intrapericardial tranexamic acid (TXA) versus intravenous TXA for efficacy and safety in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods In this single-center randomized trial, 492 patients were assigned 1:1 t...

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Principais autores: Dilnaar Tuerhong, Chen‑xi Li, Lei Yan
Format: Artigo
Jezik:Inglês
Izdano: BMC 2026-05-01
Serija:BMC Anesthesiology
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Online dostop:https://doi.org/10.1186/s12871-026-03872-2
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