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A randomized controlled trial comparing romosozumab and denosumab in elderly women with primary osteoporosis and knee osteoarthritis

Abstract We compared the efficacy of romosozumab and denosumab in elderly women with primary osteoporosis and knee osteoarthritis in a randomized controlled trial. A total of 112 participants aged 75–90 years were randomized equally into the romosozumab and denosumab groups. Among these, 49 and 52 p...

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Principais autores: Yasumori Sobue, Hironobu Kosugiyama, Shuji Asai, Yoshikazu Ogawa, Minoru Yoneda, Koji Maruyama, Mariko Kaneko, Tomonori Kobayakawa, Kenya Terabe, Mochihito Suzuki, Ryo Sato, Yusuke Ohno, Junya Hasegawa, Takaya Sugiura, Masahiko Ando, Yachiyo Kuwatsuka, Naoki Ishiguro, Shiro Imagama
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-07-01
Serier:Scientific Reports
Fag:
Denosumab
Knee osteoarthritis
Osteophyte
Osteoporosis
Romosozumab
Online adgang:https://doi.org/10.1038/s41598-025-05187-7
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