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A novel AllGlo probe-quantitative PCR method for detecting single nucleotide polymorphism in CYP2C19 to evaluate the antiplatelet activity of clopidogrel

Abstract CYP2C19 gene has multiple single nucleotide polymorphism (SNP), which is the major determinant for clopidogrel treatment responses. Therefore, CYP2C19 SNP detection is essential for predicting clopidogrel efficacy. Currently, there is still no quick and effective method for routine detectio...

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Autores principales: Hongwei Li, Yizhen Fang, Yongquan Chen, Yuning Lin, Zanxi Fang, Zhiyuan Lin, Huabin Xie, Zhongying Zhang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2024-01-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-024-52540-3
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