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Prognostic significance of novel katG mutations in Mycobacterium tuberculosis

Background: By using whole genome sequencing (WGS), researchers are beginning to understand the genetic diversity of Mycobacterium tuberculosis (MTB) and its consequences for the diagnosis of multidrug-resistant tuberculosis (MDR–TB) on a genomic scale. The Global Consortium for Drug-resistant TB Di...

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Autori principali: F Valafar, S M Ramirez-Busby, J Torres, Lynthia V Paul, T C Rodwell, T C Victor, C Rodrigues, M T Gler, V Crudu, T Catanzaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Medknow Publications 2015-01-01
Serie:International Journal of Mycobacteriology
Soggetti:
Tuberculosis
Drug resistance
Isoniazid
katG
Novel mutations
Positive selection
Prognosis
Whole genome sequencing
Accesso online:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=51;epage=52;aulast=Valafar;type=0
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