The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

Diacylglycerol acyltransferase (DGAT) catalyzes the final step in triglyceride (TG) synthesis. There are two isoforms, DGAT1 and DGAT2, with distinct protein sequences and potentially different physiological functions. To date, the ability to determine clear functional differences between DGAT1 and...

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Detalhes bibliográficos

Principais autores:	Jenson Qi, Wensheng Lang, John G. Geisler, Ping Wang, Ioanna Petrounia, Selyna Mai, Charles Smith, Hossein Askari, Geoffrey T. Struble, Robyn Williams, Sanjay Bhanot, Brett P. Monia, Shariff Bayoumy, Eugene Grant, Gary W. Caldwell, Matthew J. Todd, Yin Liang, Micheal D. Gaul, Keith T. Demarest, Margery A. Connelly
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2012-06-01
Colecção:	Journal of Lipid Research
Assuntos:	diacylglycerol acyltransferase triglyceride synthesis very low density lipoprotein triglyceride liquid chromatography tandem mass spectrometry 13C3-D5-glycerol 13C18-oleic acid
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S002222752031703X
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