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Aging RNA granule dynamics in neurodegeneration

Disordered RNA-binding proteins and repetitive RNA sequences are the main genetic causes of several neurodegenerative diseases, including amyotrophic lateral sclerosis and Huntington’s disease. Importantly, these components also seed the formation of cytoplasmic liquid-like granules, like stress gra...

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Auteurs principaux: Kevin Rhine, Norah Al-Azzam, Tao Yu, Gene W. Yeo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-09-01
Collection:Frontiers in Molecular Biosciences
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fmolb.2022.991641/full
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