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Cardiovascular health in pediatric patients with X-linked hypophosphatemia under two years of burosumab therapy

IntroductionX-linked hypophosphatemia (XLH) is caused by an inactivating mutation in the phosphate-regulating endopeptidase X-linked (PHEX) gene whose defective product fails to control phosphatonin fibroblast growth factor 23 (FGF23) serum levels. Although elevated FGF23 levels have been linked wit...

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Principais autores: Avivit Brener, Roxana Cleper, Guy Baruch, Ehud Rothschild, Michal Yackobovitch-Gavan, Gil Beer, Leonid Zeitlin, Livia Kapusta
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Endocrinology
Fag:
cardiac function
echocardiogram
elevated blood pressure
FGF23
left ventricular hypertrophy
X-linked hypophosphatemia
Online adgang:https://www.frontiersin.org/articles/10.3389/fendo.2024.1400273/full
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