Abnormal T-Cell activation and cytotoxic T-Cell frequency discriminate symptom severity in myalgic encephalomyelitis/chronic fatigue syndrome

Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating but poorly-understood disease. ME/CFS symptoms include immune system effects alongside incapacitating fatigue and post-exertional disease exacerbation. Symptom severity can range from mild to severe and...

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Detalhes bibliográficos

Principais autores:	Ji-Sook Lee, Eliana Lacerda, Caroline Kingdon, Ella Abken, Giada Susannini, Hazel M. Dockrell, Luis Nacul, Jacqueline M. Cliff
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Journal of Translational Medicine
Assuntos:	ME/CFS Symptom severity CD8+ T cells Mucosal-associated invariant T cells Cytotoxicity T cell activation
Acesso em linha:	https://doi.org/10.1186/s12967-025-07507-x
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