Construction of an El Tor Biovariant Vibrio cholerae Strain Capable of Type II Cholera Toxin Hyperproduction and Determining the Optimal Conditions for the Production of This Protein

Introduction of Tn5-Mob (KmR) transposon into the chromosome of the toxinogenic V. cholerae strain MAK757 El Tor biovar was shown to result in the emergence of insertion mutants containing an altered genome of CTXφ prophage. The reorganization ofthe latter was expressed in the deletion of four genes...

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Bibliografiske detaljer

Principais autores:	A. A. Goryaev, E. Yu. Shchelkanova, Yu. V. Lozovsky, I. V. Touchkov, N. I. Smirnova
Format:	Artigo
Sprog:	Russo
Udgivet:	Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2008-02-01
Serier:	Проблемы особо опасных инфекций
Fag:	the cholera agent a cholera toxin hyperproducing strain prophage ctxφ genome reorganization tn5-mob transposon
Online adgang:	https://journal.microbe.ru/jour/article/view/1075
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