Comparative evaluation of AlphaFold2 and disorder predictors for prediction of intrinsic disorder, disorder content and fully disordered proteins

We expand studies of AlphaFold2 (AF2) in the context of intrinsic disorder prediction by comparing it against a broad selection of 20 accurate, popular and recently released disorder predictors. We use 25% larger benchmark dataset with 646 proteins and cover protein-level predictions of disorder con...

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Hlavní autoři:	Bi Zhao, Sina Ghadermarzi, Lukasz Kurgan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Association for the Advancement of Science (AAAS) 2023-01-01
Edice:	Computational and Structural Biotechnology Journal
Témata:	Intrinsic disorder Intrinsically disordered protein AlphaFold2 Prediction Deep learning Disorder content
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2001037023002143
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