Analytical validation of a hybrid-approach combining tumor-informed and tumor-agnostic bespoke ctDNA panel assay for the sensitive detection of minimal residual disease.

Minimal residual disease (MRD) is a small group of cancer cells not eliminated by anti-cancer treatment. Because of its small size, conventional imaging system may not be able to detect the MRD in routine clinical practice. Although the liquid biopsy tests can detect the circulating tumor DNA (ctDNA...

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Principais autores:	Sunghoon Heo, Seon-Kyu Ham, Hayoon Lee, Bom Han, Hanseong Roh, Seongmun Jeong, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Tae-You Kim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2025-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0334282
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