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Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neurons

Abstract Induced pluripotent stem cell (iPSC) technology, in combination with electrophysiological characterization via multielectrode array (MEA), has facilitated the utilization of iPSC-derived motor neurons (iPSC-MNs) as highly valuable models for underpinning pathogenic mechanisms and developing...

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Gardado en:
Principais autores: Meimei Yang, Daofeng You, Gang Liu, Yin Lu, Guangming Yang, Timothy O’Brien, David C. Henshall, Orla Hardiman, Li Cai, Min Liu, Sanbing Shen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-10-01
Series:Scientific Reports
Assuntos:
iPSC-derived motor neurons
Extracellular matrix
Poly-l-ornithine
Matrigel
Polyethyleneimine
Multielectrode array
Acceso en liña:https://doi.org/10.1038/s41598-024-77710-1
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