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Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?

Heparan sulfate (HS) and heparin are glycosaminoglycans (GAGs) that are heterogeneous in nature, not only due to differing disaccharide combinations, but also their sulfate modifications. HS is well known for its interactions with various growth factors and cytokines; and heparin for its clinical us...

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Hlavní autoři: Brooke L. Farrugia, Megan S. Lord, James Melrose, John M. Whitelock
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2015-03-01
Edice:Molecules
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On-line přístup:http://www.mdpi.com/1420-3049/20/3/4254
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