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Protective effects and possible mechanisms of matrine-type alkaloids (matrine and oxymatrine) in animal models of ulcerative colitis: a preclinical systematic review and meta-analysis

BackgroundMatrine and oxymatrine are bioactive alkaloids from Sophora species with reported anti-inflammatory and antioxidant effects in ulcerative colitis (UC). However, their overall efficacy has not been systematically evaluated.MethodsDatabases including PubMed, EMBASE, Web of Science, Scopus, C...

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Principais autores: Shuqing Lu, Hanjian Yang, Shiying Wang, Jiahui Ye, Suiping Huang, Linkun Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-07-01
coleção:Frontiers in Pharmacology
Assuntos:
inflammation
matrine
meta-analysis
oxymatrine
preclinical study
ulcerative colitis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2026.1870457/full
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