Immunoinformatics design of a multi-epitope vaccine for Chlamydia trachomatis major outer membrane proteins

Abstract Chlamydia trachomatis (CT) remains a significant infectious cause of blindness and sexually transmitted infections worldwide. The objective and novelty of this study lie in using different serovars of CT to design a broad-spectrum multi-epitope vaccine that might confer immunity against dif...

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Bibliografische Detailangaben

Hauptverfasser:	Seema Shetty, Swagatika Dash, Avinash Kumar, Shashidhar Vishwanath, Suvarna G. Kini, Angela Brand
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-12-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Multi-epitope vaccine Chlamydia trachomatis Immunoinformatics T-cell and B-cell epitopes Molecular dynamics simulations Immune simulation
Online-Zugang:	https://doi.org/10.1038/s41598-024-81736-w
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