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Personalized sirolimus regimen for vascular malformations: a retrospective analysis of VASE cohort

Abstract Background The mTOR inhibitor Sirolimus was shown to improve symptoms in patients with slow-flow vascular malformations, but long-term continuous use is limited by cumulative toxicity. A personalized approach with intermittent regimens may offer similar efficacy with fewer adverse effects (...

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Detalles Bibliográficos
Principais autores: Emmanuel Seront, An Van Damme, Julien Coulie, Miikka Vikkula, Laurence M. Boon
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-12-01
Series:Orphanet Journal of Rare Diseases
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Acceso en liña:https://doi.org/10.1186/s13023-025-04151-y
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