A pragmatic, multicenter, randomized trial comparing morning versus evening dosing of adjuvant endocrine therapy (REaCT-CHRONO Study)

Abstract The time of day of administration (chronotherapy) of certain medications can affect both their toxicity and efficacy. In this pragmatic, multicenter trial, women starting adjuvant endocrine therapy (ET) for hormone receptor-positive early-stage breast cancer were randomized (1:1) to either...

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Detalhes bibliográficos

Principais autores:	M. F. Savard, M. Ibrahim, D. Saunders, G. R. Pond, T. L. Ng, A. A. Awan, S. Sehdev, N. Alqahtani, L. Vandermeer, F. MacDonald, A. A. Beltran-Bless, L. Fallowfield, M. Clemons
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-05-01
coleção:	npj Breast Cancer
Acesso em linha:	https://doi.org/10.1038/s41523-025-00762-7
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