Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis

Citrate, generated in the mitochondria, is a key metabolite that might link metabolism with signaling, chromatin structure and transcription to orchestrate mesenchymal stem cells (MSCs) fate determination. Based on a detailed morphological analysis of 3D reconstruction of mitochondria and nuclei in...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Claudia Morganti, Massimo Bonora, Saverio Marchi, Letizia Ferroni, Chiara Gardin, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton, Barbara Zavan
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2020-04-01
Цуврал:	Cells
Нөхцлүүд:	osteogenesis citrate α-ketoglutarate mitochondrial metabolism mesenchymal stem cells mitochondria-nucleus communication
Онлайн хандалт:	https://www.mdpi.com/2073-4409/9/4/1034
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!