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AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice

Summary: Existing therapies for inflammatory bowel disease that are based on broad suppression of inflammation result in variable clinical benefit and unwanted side effects. A potential therapeutic approach for promoting immune tolerance is the in vivo induction of regulatory T cells (Tregs). Here w...

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Detalhes bibliográficos
Principais autores: Jeremy A. Goettel, Roopali Gandhi, Jessica E. Kenison, Ada Yeste, Gopal Murugaiyan, Sharmila Sambanthamoorthy, Alexandra E. Griffith, Bonny Patel, Dror S. Shouval, Howard L. Weiner, Scott B. Snapper, Francisco J. Quintana
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-10-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124716313559
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