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The Role of Chaperone-Mediated Autophagy in Bortezomib Resistant Multiple Myeloma

<b>Background:</b> Multiple myeloma (MM) remains incurable despite high-dose chemotherapy, autologous stem cell transplants and novel agents. Even with the improved survival of MM patients treated with novel agents, including bortezomib (Bz), the therapeutic options in relapsed/refractory MM remain...

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Tallennettuna:
Päätekijät: Nicholas Nikesitch, Patricia Rebeiro, Lye Lin Ho, Srinivasa Pothula, Xin Maggie Wang, Tiffany Khong, Hazel Quek, Andrew Spencer, Cheok Soon Lee, Tara L. Roberts, Silvia C. W. Ling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2021-12-01
Sarja:Cells
Aiheet:
multiple myeloma
resistance
bortezomib
chaperone mediated autophagy
LAMP2A
ER stress and autophagy
Linkit:https://www.mdpi.com/2073-4409/10/12/3464
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