Intraoperative magnesium sulphate as an analgesic adjunct in a multimodal, opioid-sparing protocol for canine ovariohysterectomy: a prospective, randomized, controlled, double-blind study

IntroductionMagnesium acts as a non-competitive NMDA receptor antagonist and may attenuate central sensitization. Evidence regarding its analgesic- or anaesthetic-sparing effects in dogs remains inconclusive. This prospective, randomized, blinded, controlled clinical study evaluated the effect of in...

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Principais autores:	Stefanos G. Georgiou, Filimon Diamantis, Tilemachos L. Anagnostou, Fotini A. Koutina, Evgenia Papagiorgou, Theodora Κ. Milini, Apostolos D. Galatos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-05-01
Colecção:	Frontiers in Veterinary Science
Assuntos:	analgesia dog magnesium sulphate multimodal analgesia ovariohysterectomy postoperative pain
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fvets.2026.1771080/full
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