RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM
Abstract Background Amyotrophic lateral sclerosis (ALS) is an adult-onset, fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. While pathogenic mutations in the DNA/RNA-binding protein Matrin-3 (MATR3) are linked to ALS and distal myopathy, the molecul...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-08-01
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| coleção: | Acta Neuropathologica Communications |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s40478-020-01021-5 |
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