Generation of a rhesus macaque harboring a multivalent reporter for assessing gene editing outcomes

Abstract Somatic gene editing therapies offer the potential for lasting treatments for a range of genetic disorders, with a host of therapies at various stages of clinical testing. The development of safe, effective therapies required relevant pre-clinical animal models capable of measuring on-targe...

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Principais autores:	Junghyun Ryu, Kristie Ryder, Hiroaki Naka, Jenni Tran, Brayden J. Hinrichs, Sreya Biswas, Lauren N. Rust, Sofiya Yusova, Brandy L. Dozier, Samuel M. Peterson, Jochen M. Wettengel, Carol B. Hanna, Jon D. Hennebold, Benjamin J. Burwitz, Benjamin N. Bimber
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-05-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-026-52214-2
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