Strong SARS-CoV-2 N-Specific CD8⁺ T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice

SARS-CoV-2-specific CD8⁺ T cell immunity is expected to counteract viral variants in both efficient and durable ways. We recently described a way to induce a potent SARS-CoV-2 CD8⁺ T immune response through the generation of engineered extracellular vesicles (EVs) emerging from...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Flavia Ferrantelli, Chiara Chiozzini, Francesco Manfredi, Patrizia Leone, Massimo Spada, Antonio Di Virgilio, Andrea Giovannelli, Massimo Sanchez, Andrea Cara, Zuleika Michelini, Maurizio Federico
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-02-01
Schriftenreihe:	Viruses
Schlagworte:	SARS-CoV-2 vaccines CD8<sup>+</sup> T cell immunity extracellular vesicles Nef
Online-Zugang:	https://www.mdpi.com/1999-4915/14/2/329
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