Advances in benzaldehyde lyase-catalyzed biotransformations: From enzyme engineering to industrial applications

Benzaldehyde lyase (BAL), a thiamine diphosphate (ThDP)-dependent enzyme requiring divalent cations (e.g., Mg2+), mediates enantioselective C-C bond formation and cleavage to exclusively produce (R)-configured α-hydroxy ketones. Recent integration of rational enzyme design, materials science, and gr...

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Autori principali:	Zhiyun Li, Junwei Huang, Bingrong Chen, Shilong Dou, Xiaoxia Liu, Wei Zhu, Zhiran Ju, Fener Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co. Ltd. 2026-04-01
Serie:	Green Synthesis and Catalysis
Soggetti:	Benzaldehyde lyase α-hydroxy ketones Chiral synthesis Biotransformation
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666554925001504
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