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Human platelet lysate-cultured adipose-derived stem cell sheets promote angiogenesis and accelerate wound healing via CCL5 modulation

Abstract Background A rising population faces challenges with healing-impaired cutaneous wounds, often leading to physical disabilities. Adipose-derived stem cells (ASCs), specifically in the cell sheet format, have emerged as a promising remedy for impaired wound healing. Human platelet lysate (HPL...

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Principais autores: Yueh-Chen Chen, Er-Yuan Chuang, Yuan-Kun Tu, Chia-Lang Hsu, Nai-Chen Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-06-01
coleção:Stem Cell Research & Therapy
Assuntos:
Adipose-derived stem cells
Cell sheet
Wound healing
Angiogenesis
CCL5
Acesso em linha:https://doi.org/10.1186/s13287-024-03762-9
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