Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway

Aims: Osteoarthritis (OA) is the most common chronic pathema of human joints. The pathogenesis is complex, involving physiological and mechanical factors. In previous studies, we found that ferroptosis is intimately related to OA, while the role of Sat1 in chondrocyte ferroptosis and OA, as well as...

Descripció completa

Dades bibliogràfiques

Autors principals:	Jingting Xu, Zhaoxuan Ruan, Zhou Guo, Liangcai Hou, Genchun Wang, Zehang Zheng, Xiong Zhang, Haigang Liu, Kai Sun, Fengjing Guo
Format:	Artigo
Idioma:	Inglês
Publicat:	The British Editorial Society of Bone & Joint Surgery 2024-03-01
Col·lecció:	Bone & Joint Research
Matèries:	osteoarthritis chondrocyte ferroptosis inflammation chondrocytes collagen ii intra-articular injection lipid collagen interleukin-1β rna reactive oxygen species destabilization of the medial meniscus (dmm) surgery
Accés en línia:	https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.133.BJR-2023-0250.R1
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!