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Interaction of GPER-1 with the endocrine signaling axis in breast cancer

G Protein-Coupled Estrogen Receptor 1 (GPER-1) is a membrane estrogen receptor that has emerged as a key player in breast cancer development and progression. In addition to its direct influence on estrogen signaling, a crucial interaction between GPER-1 and the hypothalamic-pituitary-gonadal (HPG) a...

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Huvudupphov: Luis Molina Calistro, Yennyfer Arancibia, Marcela Alejandra Olivera, Sigrid Domke, Rodrigo Flavio Torres
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2025-01-01
Serie:Frontiers in Endocrinology
Ämnen:
GPER-1
estrogen
hypothalamic-pituitary-gonadal axis
breast cancer
endocrine resistance
personalized medicine
Länkar:https://www.frontiersin.org/articles/10.3389/fendo.2025.1494411/full
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