Dysregulation of the hypothalamus-pituitary-adrenal axis predicts some aspects of the behavioral response to chronic fluoxetine: association with hippocampal cell proliferation

In depressed patients, antidepressant resistance has been associated with dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis but the underlying mechanisms are poorly understood. The scope of this study was to try to create HPA-related antidepressant resistance in mice and to investigate...

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Autori principali:	Wahid eKhemissi, Rai Khalid eFAROOQ, Anne Marie eLe Guisquet, Mohsen eSakly, Catherine eBelzung
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2014-09-01
Serie:	Frontiers in Behavioral Neuroscience
Soggetti:	Corticosterone Fluoxetine Hippocampal neurogenesis Antidepressant resistance unpredictable chronic mild stress dexamethazone suppression
Accesso online:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00340/full
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