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Bmi1 is expressed in postnatal myogenic satellite cells, controls their maintenance and plays an essential role in repeated muscle regeneration.

Satellite cells are the resident stem cell population of the adult mammalian skeletal muscle and they play a crucial role in its homeostasis and in its regenerative capacity after injury. We show here that the Polycomb group (PcG) gene Bmi1 is expressed in both the Pax7 positive (+)/Myf5 negative (-...

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Autors principals: Lesley G Robson, Valentina Di Foggia, Aleksandar Radunovic, Katy Bird, Xinyu Zhang, Silvia Marino
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0027116&type=printable
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