SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots
Abstract We present SpotOn, a web server to identify and classify interfacial residues as Hot-Spots (HS) and Null-Spots (NS). SpotON implements a robust algorithm with a demonstrated accuracy of 0.95 and sensitivity of 0.98 on an independent test set. The predictor was developed using an ensemble ma...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2017-08-01
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| Edice: | Scientific Reports |
| On-line přístup: | https://doi.org/10.1038/s41598-017-08321-2 |
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