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Hamster neogenin, a host-cell protein contained in a respiratory syncytial virus candidate vaccine, induces antibody responses in rabbits but not in clinical trial participants

A recombinant respiratory syncytial virus (RSV) fusion glycoprotein candidate vaccine (RSV-PreF) manufactured in Chinese hamster ovary cells was developed for immunization of pregnant women, to protect newborns against RSV disease through trans-placental antibody transfer. Traces of a host-cell prot...

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Principais autores: Ann-Muriel Steff, Chanel Cadieux-Dion, Gaël de Lannoy, Maria Key Prato, Xavier Czeszak, Bruno André, Dominique C Ingels, Marc Louckx, Walthère Dewé, Marta Picciolato, Koen Maleux, Laurence Fissette, Ilse Dieussaert
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-06-01
coleção:Human Vaccines & Immunotherapeutics
Assuntos:
neogenin
respiratory syncytial virus
fusion protein
vaccine candidate
host cell protein
chinese hamster ovary
rsv-pref
Acesso em linha:http://dx.doi.org/10.1080/21645515.2019.1693749
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