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Asymmetric cell division safeguards memory CD8 T cell development

Summary: The strength of T cell receptor (TCR) stimulation and asymmetric distribution of fate determinants are both implied to affect T cell differentiation. Here, we uncover asymmetric cell division (ACD) as a safeguard mechanism for memory CD8 T cell generation specifically upon strong TCR stimul...

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I tiakina i:
Ngā kaituhi matua: Fabienne Gräbnitz, Dominique Stark, Danielle Shlesinger, Anthony Petkidis, Mariana Borsa, Alexander Yermanos, Andreas Carr, Niculò Barandun, Arne Wehling, Miroslav Balaz, Timm Schroeder, Annette Oxenius
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2023-05-01
Rangatū:Cell Reports
Ngā marau:
CP: Immunology
CP: Cell biology
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124723004795
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