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Assessment of anti-CD20 antibody pre-treatment for augmentation of CAR-T cell therapy in SIV-infected rhesus macaques

During chronic HIV and SIV infections, the majority of viral replication occurs within lymphoid follicles. In a pilot study, infusion of SIV-specific CD4-MBL-CAR-T cells expressing the follicular homing receptor, CXCR5, led to follicular localization of the cells and a reduction in SIV viral loads i...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mary S. Pampusch, Emily N. Sevcik, Zoe E. Quinn, Brianna C. Davey, James M. Berg, Ian Gorrell-Brown, Hadia M. Abdelaal, Eva G. Rakasz, Aaron Rendahl, Pamela J. Skinner
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2023-02-01
Saila:Frontiers in Immunology
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1101446/full
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