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Porcine rotavirus type A VP8 protein: an antigen with dual functions as a subunit vaccine and serological diagnostic agent, from receptor binding to mucosal and systemic immunity

Porcine group A rotavirus (PoRVA) continues to be a significant cause of neonatal diarrhea in pigs, affecting swine production globally. VP8*, the glycan-binding domain of VP4, is crucial for viral attachment and immune activation. The dual role of VP8* makes it a promising candidate for vaccines an...

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Principais autores: Zhang Zhen, Liu Shuhua, Ma Baihe, Chen Xin, Guo Meiliang, Liang Fanxin, Li Lianrui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Virology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fviro.2026.1859126/full
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