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CRISPR genome editing using computational approaches: A survey

Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene editing has been widely used in various cell types and organisms. To make genome editing with Clustered regularly interspaced short palindromic repeats far more precise and practical, we must concentrate on the design of o...

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Principais autores: Roghayyeh Alipanahi, Leila Safari, Alireza Khanteymoori
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-01-01
Serier:Frontiers in Bioinformatics
Fag:
CRiSPR/Cas
gRNA design
on-target
off-target
computational approach
machine learning
Online adgang:https://www.frontiersin.org/articles/10.3389/fbinf.2022.1001131/full
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