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E2 regulates epigenetic signature on Neuroglobin enhancer-promoter in neuronal cells

Estrogens are neuroprotective factors in several neurological diseases. Neuroglobin (NGB) is one of the estrogen target gene involved in neuroprotection, but little is known about its transcriptional regulation. Estrogen genomic pathway in gene expression regulation is mediated by estrogen receptors...

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Главные авторы: Michela eGuglielmotto, Stefania eReineri, Andrea eIannello, Giulio eFerrero, Ludovica eVanzan, Valentina eMiano, Laura eRicci, Elena eTamagno, Michele eDe Bortoli, Santina eCutrupi
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016-06-01
Серии:Frontiers in Cellular Neuroscience
Предметы:
Epigenetic regulation
estrogen receptor
Neuroglobin
chromatin remodelling
Genomic regions
Online-ссылка:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00147/full
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