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A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts

The coronavirus disease 2019 (COVID-19) pandemic has illustrated the critical need for effective prophylactic vaccination to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Intranasal vaccination is an attractive approach for preventing COVID-19 as the nasal mucos...

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Principais autores: Michael D. Schultz, John J. Suschak, Davide Botta, Aaron Silva-Sanchez, R. Glenn King, Thomas W. Detchemendy, Chetan D. Meshram, Jeremy B. Foote, Fen Zhou, Jennifer L. Tipper, Jianfeng Zhang, Kevin S. Harrod, Sixto M. Leal, Troy D. Randall, M. Scot Roberts, Bertrand Georges, Frances E. Lund
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2022-11-01
Serier:Human Vaccines & Immunotherapeutics
Fag:
covid-19
sars-cov-2
receptor binding domain
vaccine
adenovirus vector
viral vector
intranasal
mucosal immunity
Online adgang:http://dx.doi.org/10.1080/21645515.2022.2127292
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