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SARAH Domain-Mediated MST2-RASSF Dimeric Interactions.

RASSF enzymes act as key apoptosis activators and tumor suppressors, being downregulated in many human cancers, although their exact regulatory roles remain unknown. A key downstream event in the RASSF pathway is the regulation of MST kinases, which are main effectors of RASSF-induced apoptosis. The...

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Detalhes bibliográficos
Principais autores: Goar Sánchez-Sanz, Bartłomiej Tywoniuk, David Matallanas, David Romano, Lan K Nguyen, Boris N Kholodenko, Edina Rosta, Walter Kolch, Nicolae-Viorel Buchete
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-10-01
coleção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC5055338?pdf=render
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