Cell segmentation methods for label-free contrast microscopy: review and comprehensive comparison

Abstract Background Because of its non-destructive nature, label-free imaging is an important strategy for studying biological processes. However, routine microscopic techniques like phase contrast or DIC suffer from shadow-cast artifacts making automatic segmentation challenging. The aim of this st...

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Auteurs principaux:	Tomas Vicar, Jan Balvan, Josef Jaros, Florian Jug, Radim Kolar, Michal Masarik, Jaromir Gumulec
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2019-06-01
Collection:	BMC Bioinformatics
Sujets:	Microscopy Cell segmentation Image reconstruction Methods comparison Differential contrast image Quantitative phase imaging
Accès en ligne:	http://link.springer.com/article/10.1186/s12859-019-2880-8
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