Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity
Ras proteins are membrane-bound small GTPases that promote cell proliferation, differentiation, and apoptosis. Consistent with this key regulatory role, activating mutations of Ras are present in ∼19% of new cancer cases in the United States per year. K-Ras is one of the three ubiquitously expressed...
Na minha lista:
| Principais autores: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021-06-01
|
| Serier: | Frontiers in Molecular Biosciences |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fmolb.2021.673096/full |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|