Integrated metabolomics analysis identifies distinct amino acid signatures in chronic hepatitis B patients with metabolic dysfunction-associated steatotic liver disease

BackgroundChronic hepatitis B (CHB) and metabolic dysfunction-associated steatotic liver disease (MASLD) frequently coexist and synergistically accelerate progression to end-stage liver disease. However, the metabolic differences distinguishing CHB alone from CHB with MASLD remain poorly defined.Met...

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Main Authors:	Yanping Lan, Zitao Zhou, Qunfang Huang, Xin Yang, Xinrong Lu, Renquan Jiang, Yujue He, Xinyao Yang, Detai Ye, Zixin Chen, Can Liu, Qishui Ou, Zhen Xun
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-04-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	amino acid biomarker chronic hepatitis B MASLD metabolomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1783221/full
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