Age-Dependent Redistribution of the Life-Important Enzyme in the Retina: Adult Müller Glial Cells’ Endfeet Lack Spermine Synthase Expression

Polyamine (PA) spermine (SPM) (i) plays an essential role in the function of neurons, while (ii) accumulating predominantly in glial cells by an unknown mechanism. In addition, the translocation of SPM synthesis and redistribution in the developing and maturating retinas remains unclear. Therefore,...

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Detalhes bibliográficos

Principais autores:	Astrid Zayas-Santiago, Christian J. Malpica-Nieves, José M. Santiago, Yanitza Hernández, David E. Rivera-Aponte, Miguel Méndez-González, Rüdiger W. Veh, Legier V. Rojas, Serguei N. Skatchkov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-09-01
coleção:	Biomolecules
Assuntos:	polyamines spermine spermine synthase nervous system retina glial Müller cells
Acesso em linha:	https://www.mdpi.com/2218-273X/15/10/1374
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