Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis

Abstract Background Osteoporosis is a disease threatening the health of millions of individuals. Melatonin is found to be a potential anti-osteoporosis drug. However, whether melatonin plays a role against osteoporosis at different stages of the menopause and the underlying mechanisms are unknown. M...

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Autors principals:	Huanshuai Guan, Ning Kong, Run Tian, Ruomu Cao, Guanzhi Liu, Yiyang Li, Qilu Wei, Ming Jiao, Yutian Lei, Fangze Xing, Peng Tian, Kunzheng Wang, Pei Yang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-03-01
Col·lecció:	Journal of Translational Medicine
Matèries:	Melatonin Different stages of the menopause Osteoporosis Osteogenesis Bone marrow mesenchymal stem cells
Accés en línia:	https://doi.org/10.1186/s12967-022-03341-7
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