DL-3-n-butylphthalide attenuates doxorubicin-induced acute cardiotoxicity via Nrf2/HO-1 signaling pathway

Doxorubicin (DOX) is a widely used chemotherapeutic drug known to cause dose-dependent myocardial toxicity, which limits its clinical potential. DL-3-n-butylphthalide (NBP), a substance extracted from celery seed species, has a number of pharmacological properties, such as antioxidant, anti-inflamma...

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Detalhes bibliográficos

Principais autores:	Dengke Li, Wei Zhang, Hui Fu, Xi Wang, Yanhong Tang, Congxin Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
Colecção:	Heliyon
Assuntos:	Doxorubicin Myocardial toxicity Oxidative stress Nrf2 DL-3-n-Butylphthalide
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024036752
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