SCN1A channelopathies: Navigating from genotype to neural circuit dysfunction
The SCN1A gene is strongly associated with epilepsy and plays a central role for supporting cortical excitation-inhibition balance through the expression of NaV1.1 within inhibitory interneurons. The phenotype of SCN1A disorders has been conceptualized as driven primarily by impaired interneuron fun...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2023-04-01
|
| Schriftenreihe: | Frontiers in Neurology |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1173460/full |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|